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Residents’ Corner
2 (
); 21-21

Cyclosporine-induced hirsutism

Department of Hematology, NRSMCH, Kolkata, West Bengal, India
Corresponding author: Abhishek Kumar, Department of Hematology, NRSMCH, Kolkata, West Bengal, India.
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Kumar A. Cyclosporine-induced hirsutism. J Hematol Allied Sci 2022;2:21.

A 35-year-old lady, a case of non-severe aplastic anemia diagnosed in June 2020, was treated with cyclosporine A at a dose of 5 mg/kg/day in two divided doses; achieved partial response at 9 months and continued. After 1 year, the dose of cyclosporine A was reduced to 3 mg/kg/day in two divided doses. The patient was doing well but after 18 months of cyclosporine A therapy, she noticed that there was an excess terminal hair growth over the side lock [Figure 1], upper lip [Figure 2], chin, and midsternum which affected her mood and social behavior and she isolated herself socially. The Ferriman– Gallwey hirsutism score was 10; a score of 8 or higher is regarded as indicative of androgen excess.[1] The incidence of hirsutism following cyclosporine A therapy is around 5%.[2] Cyclosporine A was tapered off gradually with other supportive care continued. The physicians must counsel and take care of this not-so-uncommon side effect of cyclosporine A that may compromise the quality of life of a patient.

Figure 1:: Excess terminal hair growth over side lock.
Figure 2:: Excess terminal hair growth over upper lip

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The authors certify that they have obtained all appropriate patient consent.

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There are no conflicts of interest.


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